Research Articles
LFF571: A New Weapon Against the Superbug Clostridium Difficile
Explore LFF571, a novel thiopeptide antibiotic showing promise against Clostridium difficile infection with its unique EF-Tu mechanism and clinical trial results.
Unveiling Bicyclomycin: How Nature Builds a Unique Antibiotic
Discover how scientists decoded the molecular masterpiece of bicyclomycin biosynthesis, a unique antibiotic effective against drug-resistant bacteria.
The Genomic Treasure Chest: Unlocking Nature's Medicine Cabinet from a Soil Bacterium
Discover how the complete genome sequence of Actinomadura parvosata subsp. kistnae reveals a treasure trove of natural products with potential for medicine and biotechnology.
The Antibiotic Enigma: How Micrococcin P1's Secret Structure Was Unlocked
Discover how scientists unlocked the structural secrets of Micrococcin P1, a potent thiopeptide antibiotic with remarkable activity against drug-resistant bacteria and unexpected therapeutic potential.
The Molecular Gymnast: How a Tiny Mutation Supercharges Nature's Macrocyclization Machine
Discover how a single amino acid mutation in the pikromycin thioesterase creates a more efficient macrocyclization catalyst for antibiotic production.